Senior Analytical Chemist (Investigator), Open to flexible working
- Contract Type
We are seeking a motivated experienced analytical chemist to join our Drug Substance and Product Analysis teams at GSK's flagship Stevenage R&D site (in Hertfordshire). As a member of our team you will lead analytical aspects aligned to the development, manufacture and supply of new small molecule drug substances.
Your role will be office and laboratory based. You will contribute to the development of the analytical control strategy for new drug substances and author key analytical documentation (including methods and specifications). You will also design and execute method development, validation and transfer experiments, author sections of regulatory submissions and develop responses to regulatory questions. You will deliver some of these tasks independently and may lead small teams to deliver others.
You will apply analytical techniques including HPLC, GC, KF and spectroscopic techniques. Your analysis will cover projects right across the development cycle from first time in human through to commercialisation. Duties will also include executing analytical work safely in accordance with GMP, working in a matrix team to ensure appropriate analytical methods are in place as required for the assessment of intermediates and drug substance and their release for clinical use. You will also be required to lead the transfer of methods to commercial manufacturing sites. You will be expected to clearly report the results of your experiments and communicate the results and your conclusions to matrix teams and management.
The role is highly technical and dynamic as you will be working in a number of multi-disciplinary project teams. You will thrive in this environment if you are able to effectively manage multiple priorities, communicate your recommendations clearly, and enjoy working in teams.
This position would be suitable for a highly motivated chemist (degree-educated; BSc or MSc) with demonstrable knowledge/experience in the application of analytical chemistry to the development of small molecule drug substances. You will have knowledge of ICH quality guidelines and understand how to apply these to define a control strategy for a new drug substance. You will have experience authoring sections of IND, CTA, MAA and NDA files and have excellent written and oral communication skills.
The successful applicant can expect excellent onward training in analytical development as well as the opportunity to collaborate with experts working in other disciplines; particularly formulation, manufacturing, regulatory and synthetic chemistry.
CLOSING DATE for applications: Monday 23rd of November 2020 (COB).
When applying for this role please draw attention to your relevant experience in analytical chemistry in your CV. The information that you provide will be used to assess your application.
GSK is a science-led global healthcare company that researches and develops a broad range of innovative medicines and brands. Our products are used by millions of people around the world, helping them to do more, feel better and live longer. Employing over 100,000 people globally, we have 71 manufacturing sites around the world.
- Relevant qualifications / experience in Chemistry (BSc or M.Chem)
- Previous experience of analytical techniques (specifically; HPLC, GC, KF and spectroscopic techniques)
- Knowledge of ICH quality guidelines and their applicability to small molecule drug substance
- Previous experience authoring regulatory submissions (eg. IND, CTA, MAA, NDA)
- Knowledge of the requirement for releasing drug substances for clinical studies
- GMP knowledge / experience
As a company driven by our values of Patient focus, Transparency, Respect and Integrity, we know inclusion and diversity are essential for us to be able to succeed. We want all our colleagues to thrive at GSK bringing their unique experiences, ensuring they feel good and to keep growing their careers. As a candidate for a role, we want you to feel the same way.
As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).
We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
Please don't hesitate to contact us if you'd like to discuss any adjustments to our process which might help you demonstrate your strengths and capabilities.
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