Molecular Biology Scientist, Open to flexible working
5 days left
- Contract Type
- Contract - interim/fixed term
An exciting 12 month contract opportunity is available to join the Functional Genomics department as part of the Genome Biology group. This group is working to unlock the genetic clues which underly human disease, thereby delivering new and better medicines. In the role you will utilise the power of CRISPR in high-throughput to enable the discovery and validation of novel disease targets.
Working in a multi-faceted, dynamic, and cutting-edge scientific environment, this laboratory-based role will give you the opportunity: a) to apply your molecular and cell biology expertise to build and support functional genomic screens, b) obtain practical experience in target identification and validation, c) work with key partners across the business and interface collaboratively across local and global matrix teams.
Key Responsibilities include, but are not limited to:
- Implementing focused or genome-wide CRISPR screens, employing physiological- and/or disease-relevant cellular models and assays.
- Developing and running phenotypic assays such as FACS and cellular imaging.
- Employing molecular characterization of samples at genomic, RNA, and protein levels.
- Working in a GLP Laboratory, and maintaining relevant standards for this environment
- Working in a matrix team environment to enable delivery of project and department objectives to the highest possible scientific standard.
- Ensuring compliance with all GSK R&D data integrity practices, ethics codes, standards and training, and safety training and practices.
- Communicating experimental findings effectively, in written and verbal formats
Success in this position will require technical knowledge as outlined in the interview, combined with excellent analytical skills and problem-solving abilities. You will need to be a real team worker, with advanced interpersonal and communication skills, able to engage stakeholders both in the department and from other groups. You will be a highly committed, enthusiastic and motivated person with a passion for learning and an inquisitive nature, which enables you to seek answers to complicated scientific questions. As this is a constantly developing field, you will need to be a quick learner, adaptable and able to deliver impact quickly with new tasks and new technologies.
Required Qualifications and experience:
- PhD or equivalent experience in genomics, molecular or cellular biology
- Extensive experience of primary cell culture
- Broad experience and in-depth knowledge in phenotypic assays including FACS
- Experience in a broad range of molecular & cellular biology techniques including vector cloning and lentivirus production
- Demonstrable experience solving scientific problems.
- Broad experience and in-depth knowledge in CRISPR gene editing at single gene or screening level
- Proven experience in immunology research
- Familiarity with genetic, proteomic, imaging, and/or other 'omics technologies
- Ability to formulate and communicate a coherent vision/research plan.
- Strong enterprise behaviour working within multidisciplinary teams.
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