Chemical Biologist, Open to flexible working

5 days left

Stevenage, Hertfordshire
02 Jun 2021
27 Jun 2021

1 Year Fixed Term Contract: Chemical Biology (UK) Team, Medicines Design, MST

Building on GSK's strategic investment in human genetic and functional genomics, a dedicated Chemical Biology team was recently established to support the delivery of our early stage pipeline of innovative medicines. Working in partnership with our Research Units, and Medicines Design organisation, our team of chemical biologists sets out to identify small molecule probes to support target identification and validation as well as assessing target tractability and informing modality selection.

An opportunity has now arisen for a chemical biologist to join the department on a fixed term basis.

Roles and Responsibilities

The role is for a laboratory-based scientist carrying out experimental work directly in support of GSK's expanding early stage discovery pipeline. The successful candidate will be fully integrated into the team and will be expected to contribute to a culture and environment of scientific excellence. The role will be highly collaborative and provide opportunity to develop insight into early stage drug discovery along with the flexibility to broaden laboratory skills at the interface between medicinal chemistry and protein sciences/screening. A key element of practical work will include involvement the laboratory's LCMS screening platform for reactive fragments.

  • Maintain high productivity in practical chemical biology.
  • Contribute to the design and implementation of experiments to address biological questions.
  • Interpret and communicate complex scientific data.
  • Integrate effectively into the chemical biology department.

Key capabilities and desired experience

  • A track record of high personal productivity working across the chemistry/biology interface, including excellent synthetic chemistry skills. Some experience of mass spectrometry and hands-on practical experience using biochemical assays and proteomic workflows would be advantageous, though not an essential requirement.
  • Knowledge of contemporary chemical biology techniques in relation to small molecule drug discovery is highly desirable, particularly with respect to target identification, validation, tractability and engagement.
  • Self-starting, proactive working style with an ability to work flexibly and manage multiple tasks simultaneously.
  • Experience of effective collaborative working in an integrated scientific setting, for example with biochemists, chemoproteomics scientists and cell biologists.
  • Ability to critically analyse, assimilate, and communicate complex scientific data.
  • Commitment to personal professional development.

Applicant profile

This position is expected to appeal to medicinal chemists or chemical biologists that have a profound interest in the practical application of chemistry to the solution of biological problems. The successful applicant can expect excellent onward training in chemical biology as well as the opportunity to collaborate with experts working in other disciplines; particularly molecular biology, high throughput chemistry and medicinal chemistry.

Please use your covering letter to highlight how you fit the applicant profile and meet the skills and competencies for the role. Your covering letter, along with your CV, will be used to assess your application.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • PhD/DPhil (or about to be awarded a PhD) in organic chemistry, medicinal chemistry, bioorganic chemistry or chemical biology OR
  • Strong industrial experience in this field

Why GSK?

At GSK, we're a company with a special purpose, to help people do more feel better and live longer. Realising our purpose starts with us. When we feel at our best, we perform at our best.

When you set out on your adventure at GSK, we make a deal. You commit to living GSK's values and expectations and performing against our Innovation, Performance and Trust priorities. And in return, GSK commits to providing the right environment for you to thrive. Put simply, it's about you being motivated to do your best work, in a place where you can be you, feel good and keep growing.

Together we build an environment where we can all thrive and focus on what matters most to each of us. It is only through the energy, dedication, drive and passion of all of us that we can be the very best for GSK, and importantly, for our patients and consumers.

As a company driven by our values of Patient focus, Transparency, Respect and Integrity, we know inclusion and diversity are essential for us to be able to succeed. We want all our colleagues to thrive at GSK bringing their unique experiences, ensuring they feel good and to keep growing their careers. As a candidate for a role, we want you to feel the same way.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it. Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.

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