Immunologist- Allergic Inflammation Discovery Performance Unit, Open to flexibility

Stevenage, Hertfordshire
06 Apr 2018
17 Apr 2018
Contract Type

Immunologist- Allergic Inflammation Discovery Performance Unit, Open to flexibility

We are offering an exciting opportunity for a highly motivated immunologist, with a strong interest in immune regulation, to join GSK's Allergic Inflammation Discovery Performance Unit (AI-DPU) in the United Kingdom (Location: GSK's site in Stevenage). The appointed immunologist will be working in a stimulating and dynamic environment, where we put great emphasis on high quality science. The AI-DPU is a multidisciplinary team of professionals exploring novel immunotherapeutic strategies for treatment of asthma.

Asthma is one of the most common chronic inflammatory diseases, with an estimated 300 million patients worldwide and an increasing prevalence, in particular among children. It is increasingly realised to be a heterogeneous disease with multiple endotypes, however a major group includes Allergic asthma which is characterized by IgE antibodies and type-2 cytokine-driven chronic airway inflammation, remodelling and airway hyperresponsiveness.

At the AI-DPU our research activities are patient-oriented and highly translational. Our unit develops targets from their initial discovery all the way to proof of efficacy studies of our drug candidates in the clinic, and therefore we have a great focus on the patients we intend to treat.

The appointed immunologist will join a target validation team focusing on immunomodulatory approaches and investigating different mechanisms underlying immune tolerance, including induction of tolerogenic dendritic cells and regulatory T cells.

Key responsibilities include;

  • Identification and validation of targets and immunomodulatory strategies using human dendritic cells, macrophages or T cells in vitro.
  • Develop, coordinate, analyse and interpret experimental studies to investigate tolerogenic mechanisms and evaluate the efficacy of novel immunotherapeutics in isolated human immune cells in vitro.
  • Maintaining knowledge of external developments in the field and contributing to and implementing project strategies.
  • Representing the DPU, Therapy Area and GSK by presenting at external scientific meetings and authoring publications in peer-reviewed journals.

During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process.

If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements please contact 0808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process.

Closing date for applications: 17th April 2018

When applying for this role, please use the 'cover letter' of the on-line application to describe how you meet the competencies for this role, as outlined in the job requirements above.
The information that you have provided in your cover letter and CV will be used to assess your application.

Thank you for your interest in this opportunity.


Basic qualifications:

  • MSc or PhD in Immunology with significant practical experience in dendritic cell and T- regulatory cell biology.

Preferred qualifications:

  • Experience in respiratory mouse models and immunological assays with isolated murine cells would be advantageous.
  • Molecular biology expertise would be an advantage

Why GSK?:

GlaxoSmithKline (GSK) is a world leading research-based pharmaceutical company that combines both individual talent and technical resources to create a platform for the delivery for strong growth in a rapidly changing healthcare market. Our mission is to improve the quality of human life by enabling people to do more, feel better and live longer.

Contact information:

You may apply for this position online by selecting the Apply now button.

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