Molecular and Cell Biologist - 12 month FTC/Secondment, Open to flexible working

Location
Stevenage, Hertfordshire
Salary
£Competitive
Posted
20 Dec 2021
Closes
23 Jan 2022
Ref
315837

GlaxoSmithKline is a world leading research-based pharmaceutical company that combines both individual talent and technical resources to create an engine for the delivery of strong growth in a rapidly changing healthcare market. Our mission is to improve the quality of human life by enabling people to do more, feel better and live longer.

We are currently seeking a scientist to join the Oncology Cell Therapy Research Unit at GSK (OCT RU) as a maternity cover, for 1 year. OCT RU is responsible for cell therapy drug discovery programmes at an early stage of research. The primary role of the OCT RU is to generate preclinical data for cell therapy drugs to support proof of concept clinical tests and further clinical development of drugs. In addition, OCT RU is increasingly responsible for the early de-risking of new targets and generating novel approaches to enhance cell therapy efficacy in solid tumours. OCT RU works in close collaboration with GSK business partners to deliver their objectives.

The successful individual would join an in vivo line and support in vivo and ex vivo studies. It would also have the opportunity to contribute to the design and execution of oncology cell therapy programmes, that will ultimately save the lives of the patients we serve. This lab-based position will open-up future prospects in the oncology research and development field for the right individual, as well as offering the opportunity to work cross functionally with a variety of teams at GSK.

Key Responsibilities include, but are not limited to:

  • self-motivated individual who can work independently and as part of a team to theoretically and experimentally address key scientific questions around early cell therapy programmes. 
  • experience in any or all of the following; drug discovery, target validation, oncology models and immunology.
  • predominantly lab-based and as such should reflect a wide range of technical skills and a strong track record of delivering decision-driving scientific data. 
  • background in cell and / or molecular biology and relevant techniques the individual will be an essential contributor to a team that is focused on generating data to drive key decisions for oncology cell therapy discovery programmes.  
  • accountable for generating high quality, robust data to support findings. 
  • use initiative, be open to the ideas of others, and willing to accept responsibilities outside of your core job description.  
  •  expected to develop credibility with colleagues across GSK R&D, perform data analysis, record keeping and reporting of results to corporate databases to agreed timelines and to give oral presentations of results at programme, group and departmental meetings.
  • The candidate must be a creative, innovative self-starter, with excellent verbal and written communication skills, and the ability to work effectively in team and matrix environments.

Closing Date for Applications: January 23rd, 2022

Please take a copy of the Job Description, as this will not be available post closure of the advert. 

When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process.  If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact 0808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • Life science graduate plus relevant experience (BSc Biological Sciences or equivalent)
  • Experience working on T-cells
  • Hands-on experience in cell biology and molecular biology (PCR, western blot, molecular cloning)
  • Proficient in aseptic cell culture and transfection of cells
  • Experience in protein-based ELISA (eg MSD) assays and flow cytometry
  • Track record of showing initiative, problem-solving and high learning agility
  • Self-motivated, well organised with the ability to perform experiments independently
  • Team player with ability to prioritise work supporting multiple programs and to achieve group objectives
  • Maintenance of accurate and clearly written laboratory notebooks and database records
  • Excellent communication skills

Preferred Qualifications:

If you have the following characteristics, it would be a plus but not essential:

  • Newly qualified PhD or relevant post MSc experience Background in basic cancer research and immunology
  • Experience with in vivo models
  • Immunology background and experience working with cell therapies like CAR/TCR T cells
  • Experience performing lentiviral vector design and lentiviral production
  • Experience in CRISPR gene editing and generating stable cell lines
  • Experience working with engineered T-cells (CAR/TCR), primary cells or other cell therapies
  • Drug discovery experience

Why GSK?

GSK is a place where outstanding people do amazing things. As a science-led global healthcare company, we exist to help people do more, feel better, live longer. This special purpose – along with our goal of being one of the world’s most innovative, best performing and trusted healthcare companies – helps us attract some of the best and brightest minds in the world.

We take pride in providing access to all and continually focus on our opportunity and obligation to do more to improve inclusion and diversity: for our people inside GSK; in the way we do business; and in the communities where we operate. 

We want our company to be a place where diversity of people and thought is valued everywhere and where we’re all able to be ourselves and feel a sense of belonging. An inclusive organization where we all feel valued, engaged and supported, knowing that our work makes an important contribution to our mission. Reinforced by our clear values and expectations, it is part of our DNA. Together we achieve extraordinary things for our patients and consumers, who rely on us each and every day.

As a company driven by our values of Patient focus, Transparency, Respect and Integrity, we know inclusion and diversity are essential for us to be able to succeed. We want all our colleagues to thrive at GSK bringing their unique experiences, ensuring they feel good and to keep growing their careers.  As a candidate for a role, we want you to feel the same way.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it.  Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.

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