Manager - Research Portfolio Decision Sciences, Open to flexibility

Brentford (City/Town), London (Greater)
31 Oct 2018
12 Nov 2018
Contract Type

Manager - Research Portfolio Decision Sciences, Open to flexibility

GSK R&D is entering an exciting phase of culture change in how we approach decision-making, portfolio analytics and insights to drive informed portfolio trade-offs. A critical success factor for improving decision making will be in providing decision makers with the right insights from robust portfolio analyses, including option generation, as part of routine decision making. With the focus on genetic evidence to improve success rates as a critical pillar of the new R&D strategy, we're looking for outstanding talent to help drive a new approach to portfolio decision-making and integrate standard portfolio management data/tools with scientific insights and analyses. Are you ready to undertake this challenge? Read below to find out more!

The Opportunity ...

This is a high-profile role that entails significant interaction with R&D functional leaders (e.g., Target Sciences, DPU Heads, PTS Leaders, Regulatory, etc.) and exposure to key investors (e.g. Corporate Development, Commercial Franchises, Manufacturing, etc.) across the organisation. You'll be responsible and accountable for delivery of the analytics required to evaluate investments for the discovery pipeline in a portfolio-wide context, and provide the data for leaders to assess performance of individual programmes (e.g. lead series, targets, programmes), DPUs, and the TAU. These analytics will be necessary to support decisions on program initiation and progression, resource allocation across Pharma, funding, and TAU/DPU strategy.The ability to manage projects, frame issues, problem-solve (both creatively and analytically), synthesise analyses and present findings to senior leadership will be key to success. You;ll enable decision making through rigorous, fact based quantitative analysis and the synthesis of insights into actionable recommendations.

You'll be an important contributor to therapeutic and disease area strategy and performance, and will lead discussions with business partners and decision-makers on likely trade-offs and potential scenarios, strategic opportunities, and gaps. You'll also be accountable for portfolio-related analyses and the information flow between Program Teams and therapeutic area leadership for portfolio-related matters and ensuring continuous data and information flow between Program Teams, TAUs, the Platforms, Finance and Portfolio Operations.

You'll work closely with R&D teams (Target Sciences, DPUs, PTS, etc.) and across the organisation (corporate strategy, business development, finance, Global Franchises, etc.) to develop integrated assessments and lead aligned portfolio optimisation exercises based on complicated analytics with the ability to clarify and communicate outcomes to facilitate decision-making at senior R&D Leadership.

We're looking for ...

You're a portfolio management expert who is a change agent and innovative thinker who will monitor the external environment for advances in data and technology that could be applied to portfolio decision making at GSK to create a competitive advantage through improved data driven insights. You're intellectually curious with a track record of seeking out novel solutions to both project-specific and portfolio wide issues and demonstrates a high level of energy, enthusiasm and commitment.

Project and portfolio teams in discovery research work on innovative targets in the absence of any pre-clinical or clinical data. Individual programmes are considered from the perspective of the selected pathway in comparison to other targets under investigation for the respective disease area. Thus, systematic risk and probability analysis incorporates evaluative techniques focused on candidate quality, modality, developability, tractability, and other metrics of discovery research.

This new group will be known for 5 things;

  1. Data-driven portfolio insights using internal and external lenses
  2. An objective perspective on GSK's portfolio versus competitors
  3. Driving challenging conversations in an open and constructive manner
  4. Utilising cutting-edge data trends/technology capabilities and applying to portfolio decision making; and
  5. Driving organisational learning from decision making

Key Responsibilities ...

  • Responsible for providing analytics based objective feedback, ensuring alignment and a consistent approach to CET, FRC, and R&D governance (mPIB, aPIB, SRB, DIB, etc.). They are accountable to the TAU/Franchise and to the governance bodies through the Strategy and Portfolio team. These analyses may include:
    • Visualisation and critical assessment of current and future state of discovery portfolio facilitating decision making and optimisation of resources and capabilities across Pharma through objective data analyses
    • Developing and recommending appropriate trade-off, risk taking, and other recommendations based on data driven insights
    • External insights, including benchmarking context and enterprise R&D portfolio context to guide and drive investment management
    • Further develop and apply advanced analytics to inform and shape decision making by program teams and senior leadership (e.g., scenario analysis)
  • Support portfolio assessments and support portfolio and indication level prioritisation and sequencing efforts based upon scientific/clinical/strategic/operational/financial factors with the ability to facilitate portfolio trade-off discussion amongst senior leaders. Ensure a coordinated approach across DPUs and key partner platform groups (e.g. PTS) to prioritise and deliver the portfolio in an optimal manner.
  • Work with senior portfolio colleagues to review current Research activities and recommend areas of short-term and longer-term focus from a Disease area, TA, modality and pipeline composition perspective and offer risk mitigation approaches to optimise the portfolio
  • Drives business efficiency, stays current, anticipate internal and external drivers, and opportunities to implement cross-functional strategies to maximise productivity and efficiency through use of global corporate standards, development and utilisation of strategic alliances with external partners
  • Supports discovery teams navigate the structures which include data driven early stage portfolio decision making and budget allocation boards and processes. This includes target and candidate selection decisions.
  • Exhibits a genuine excitement for science and what a specific target can do to interfere with a disease (symptoms, disease modification) and how it is subsequently developed into a medicine.
  • Provide strategic direction including target validation, therapeutic window (ESP), modalities and tractability.

Our Commitment ...

At GSK we are all inspired by the difference we make and challenge ourselves every day to improve the lives of patients and consumers. That's why we have created an environment where everyone feels valued, is able to develop, contribute to our mission and be proud of what we achieve.

To support you in achieving your role and career ambitions you'll be given the opportunity to:

  • Play an important role in delivering our mission
  • Be an essential part of a diverse, global team
  • Develop others as part of your own professional growth

We look forward to receiving your application !

Closing date for applications:12th Nov 2018.

When applying for this role, please use the 'cover letter' of the on-line application to clearly describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter will be used to assess your application.

During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process.

If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements please contact 0808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process.

Thank you for your interest in this opportunity.


Why You?

Basic qualifications:

  • Bachelor's Degree in scientific discipline
  • Established experience in the pharmaceutical or biotech industry
  • Experience in R&D, commercial, business and/or corporate development/consulting
  • Pharmaceutical Industry Acumen - ability to define, develop and implement business solutions based on trends, opportunities, needs and market direction within pharmaceutical industry and health care environment
  • General understanding of the drug discovery process from target identification through proof-of-concept validation
  • Ability to provide analytic support to ensure the discovery portfolio is well balanced with respect to the potential risks and rewards (e.g., ability to balance well-understood mechanism with exciting but unvalidated targets)
  • Solid comprehension of discrete choice modelling, linear and nonlinear optimisation, decision trees, Monte Carlo simulations a plus
  • Participate in decision making through rigorous, fact based quantitative analysis and the synthesis of insights into actionable recommendations
  • Ability to analyse a wide variety of data, including financial data to inform strategic decision making
  • Scientific background along with ability to incorporate financial and commercial characteristics of programs within a broad complex portfolio and to distill insights
  • Ability to solve complex problems through data analytics and in insight generation from complex data sets.
  • Ability to employ highly sound technical and business judgment in solving complex business problems with high risk/impact to the organization.
  • Team player with proven facilitative leadership skills in a cross-functional global team environment with ability to influence and align stakeholders.
  • Ability to create and communicate presentations to internal leadership and external partners
  • Ability to synthesise information from multiple sources, communicate ideas and data both verbally and written in a persuasive and appropriate manner in multi-cultural environment
  • Intellectually curious and track record of seeking out novel solutions to both project-specific and portfolio wide issues through external accreditation, networking, etc.
  • High level of energy, enthusiasm and commitment.
  • Experience with bioinformatics (transcriptomics, proteomics, and metabolomics) a plus

Preferred qualifications:

  • MBA or PhD degree in scientific or business discipline

Why GSK?:

GSK is a science-led global healthcare company. We research and develop a broad range of innovative products in three primary areas of Pharmaceuticals, Vaccines and Consumer Healthcare. We have a significant global presence with commercial operations in more than 150 countries, a network of 89 manufacturing sites, and large R&D centres in the UK, USA, Belgium and China.

At GSK we are leaders in what we do - our pharmaceuticals business is made up of innovative and established medicines and holds leading positions in respiratory disease and HIV, in 2015 we distributed more than 690 million doses of vaccines to over 150 countries, and our Consumer Healthcare group has a portfolio of some of the world's most trusted and best selling brands. As a company our mission is to help people do more, feel better, live longer.

To find out more about life at GSK, click here.

Contact information:
You may apply for this position online by selecting the Apply now button.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK HR Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

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